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老年人震颤麻痹综合症又称原发性帕金森病.慢性神经系统退行性疾病。
因中脑黑质和纹状体的神经介质多巴胺减少,导致基底节中多巴胺能和乙酰胆碱能活性失去平衡,出现临床综合症.表现为在行走,兴奋和焦虑时出现静止性震颤,肌强直“呈齿轮样”,动作迟缓,呼吸不畅,发音障碍,唾液、汗及皮脂分泌增多,发热,下肢水肿及精神忧郁.治疗早期采用理疗及医疗体操,维持日常生活能力和工作能力.后期服用左旋多巴、多巴胺激动剂及抗胆碱能药。
Alsoknown as idiopathic Parkinson's disease. Chronic nervous system degenerative diseases. Because in the substantia nigra and striatum reduced neurotransmitter dopamine, leading to basal ganglia, dopamine and acetylcholine activity can be out of balance, have clinicalsyndrome. Manifestations in walking, excitement and anxiety when resting tremor,musclerigidity, "was gear-like" movements, retardation, shortness of breath, dysphonia,saliva, sweat and sebum secretion increased, fever, leg edema, and mental depression. Treatment of early adopters physical therapy and medical gymnastics, maintaining activities of daily living and work ability. the latter part of taking L-dopa, dopamine agonists and anticholinergic drugs.